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However, across many checkpoint-focused AD studies that primarily target oxidative stress, A clearance, or neuroinflammatory checkpoints, the field has only rarely measured a complete ferroptosis signaturethat is, simultaneous assessment of iron-dependent lipid peroxidation together with GPX4/SLC7A11 and ACSL4/LPCAT3 alterations, combined with ferroptosis-selective rescue experiments (e.g., ferrostatin-1, liproxstatin-1, or FSP1 activation)

Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers

These data align with VKORC1L1s intracellular localization at the ER, a central site of lipid peroxidation 41,42

As an alternative to mAbs, B cell-targeted chimeric antigen receptor T cells are also explored for the treatment of B cell-mediated autoimmune diseases

Montagnese et al., 2013)