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Patients are monitored for symptom change, weight change, quality of life, and diabetes management with blood samples drawn to test for HbA1c levels every 6 months for 24 months

The transgenic plants showed more accumulation of MDA compared with WT under cold stress, which suggested a higher degree of lipid peroxidation in transgenic plants (Figure 7B)

Mtb-secreted antigens (PPE36, EspC, or Rv1987), heat-shock proteins (Hsp16.3), or genes like Rv2882c have been demonstrated to polarize macrophages in vitro or in mouse models, via the activation of crucial intracellular processes and the generation of soluble factors (Guo et al., 2019

However, annexin V labels apoptotic cells independently of the apoptotic pathways they underwent and as extrinsic apoptosis does not involve mitochondrial disruption it can be a plausible explanation for these results

Plant Physiol 169:30023020