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Improvements in blood cell counts can be seen quickly, while neurological symptoms may take longer to improve, sometimes several weeks or months

Sasaki H, Sato H, Kuriyama-Matsumura K, Sato K, Maebara K, Wang H, et al

Therefore, only a responsible long-term application is able to help patients achieve good results

Therapeutic strategies aiming at iron metabolism as a possible target in MDS and AML can be roughly distributed in four approaches: reduction of iron required for cellular functions via iron chelation, modulation of proteins involved in iron metabolism, induction of ferroptosis und exploitation of iron proteins for the delivery of antileukemic drugs ( Figure 3 )

and a poor regulatory environment exists