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Description

These results hint that GSTA1 directly binds to FABP1, thereby promoting the degradation of FABP1, while upregulation of GSTA1 increases mRNA (Figure 6F) but decreases the protein level of FABP1 (Figure 6G), indicating a negative feedback mechanism

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CD38 Pathway: CD38, an ectoenzyme that increases with age, is one of the largest consumers of cellular NAD+

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DeFronzo RA, Goodman AM (1995): Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus

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Cancer cell 16 , 510520 (2009)

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