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Early-phase clinical trials should assess safety and tolerability in both healthy volunteers and patient populations, supported by systematic monitoring of adverse events

In PD, the M1 phenotype may be induced by -syn aggregates, signaling through Toll-like receptors (TLR), releasing cytokines and neurotoxic molecules that promote cytotoxic responses, leading to persistent neuroinflammation (Li et al., 2021a)

Kowalczyk, E

Organ Protection and Systemic Stability : In systemic toxicity and organ injury research, BPC-157 has been observed to protect the liver, pancreas, and kidneys from induced damage

Values are the average of three independent experiments performed in triplicateSEM