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Phytate chelation of transition metals can reduce metal-catalysed radical formation, offering a secondary antioxidant benefit, while saponins have been reported to modulate lipid metabolism and to enhance endogenous antioxidant defences (increased hepatic SOD and GPx) and to attenuate proinflammatory mediators (IL 6, TNF- ) (Reference Djikeng, Djikeng and Womeni30,Reference Chen, Yuan and Xu31)

Intravaginal gene Silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

Tournissac M, Vandal M, Tremblay C, Bourassa P, Vancassel S, Emond V, et al

Elife 10, e62174

After fixation, cells were incubated with 50 mM ammonium chloride (NH 4 Cl) for 10 min