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3 Once activated by infection, neutrophils are rapidly recruited to sites of inflammation in the lungs, where they produce and secrete cytokines, enzymes, including elastase (NE), reactive oxygen species (ROS) by oxidative burst, and finally release DNA to form neutrophil extracellular traps (NETs)

10.1523/JNEUROSCI.3968-04.2004 150 YangC.WangC.WangM.QinX.HaoG.KangM.et al (2021)

These cells secrete various mediators that are directly responsible for the progression of allergy and bronchial obturation in asthma ( de novo synthesized prostaglandin D2 (PGD2), leukotriene C4 (LTC4), adenosine, and ROS are released from mast cell granules ( Figure 1 )

This method is referred to as the free capture biotin-streptavidin assay method, and it is vulnerable to biotin interference

8,9 Hyperphosphorylated tau detaches from microtubules and sticks to other tau molecules, generating threads that eventually unite to create tangles inside neurons, known as NFTs