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In individuals with confirmed B12 deficiency, correction may help normalise homocysteine metabolism, as deficiency has been associated with elevated homocysteine levels

(259) found that in the colitis rats, the expression level of the antiapoptotic protein Bcl-2 was dramatically reduced, whereas that of the proapoptotic protein Bax was significantly elevated

Lee HC, Feng L, Oriabure O, Graham V, Chen W, Badillo M, Lu R, Lee HJ, Jain P, Manasanch EE, Orlowski RZ, Wang ML

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Oxidative stress, the action of damaging chemicals known as reactive oxygen species, is of particular interest as of late as evidenced by the ever increasing body of research showing how threatening this processes is