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Description

cyclophosphamide is initially administered at a low dose and slowly increased based on the cell counts during the nadir phase

Critically, it does not bind the GH receptor in the same way as full-length GH, so it does not elevate IGF-1 or affect glucose homeostasis

This interaction may lead to changes in the receptor's structure, initiating a series of molecular events that may activate signal transduction pathways within the target cells