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Frontiers in behavioral neuroscience

Furthermore, ccRCC cells rely heavily on the GSH/GPX-4 pathway to defend against lipid peroxidation and the threat of ferroptosis

Physiol Res 50(6):537546 Bai J, Luo Y, Zhanchun S, Fan W, Wang Z, Luan T (2013) Effects and the mechanisms of chrysin on sepsis-associated acute lung injury of rats chrysin inhibits acute lung injury

Furthermore, due to the intracellular micro-environmental difference between normal and tumor cells, amifostine can be absorbed into normal cells (46) and have a protective effect

While enhanced alcohol metabolism may seem protective, elevated CYP2E1 accelerates ethanol oxidation, resulting in higher acetaldehyde production and excessive reactive oxygen species (ROS) generation, including hydroxyethyl radicals, superoxide anions, and hydroxyl radicals [27, 28]