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*Correspondence: Amirhossein Tamimi [email protected] ORCID: Amirhossein Tamimi orcid.org/0000-0002-0228-3409 Mona Javid orcid.org/0000-0003-1361-0812 Nasrin Sedighi-Pirsaraei orcid.org/0000-0002-4595-5973 Arian Mirdamadi orcid.org/0000-0002-6608-8477 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

4 Discussion In this network meta-analysis, selenium supplementation during the treatment of HT patients effectively reduced TPOAb (SMD:-2.44, 95% CI:-4.19, -0.69) and TgAb (SMD: -2.76, 95% CI:-4.50, -1.02) levels

332,333 In addition, fibrinogen level is a more specific indicator of thrombosis risk, since excess fibrinogen in circulation increases the likelihood of clot formation