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doi: 10.1038/ncomms9329 91 LyonR

My two cents

As a selective substrate site-targeting inhibitor of nicotinamide N-methyltransferase (NNMT) the cytosolic enzyme responsible for the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor 5-Amino-1MQ is studied as a tool compound for investigating NNMT enzyme activity, NAD salvage pathway interactions, and methylation pathway dynamics in controlled in-vitro experimental systems

Specifically they all made substantial contributions to the conception or design of the work, the acquisition, analysis or interpretation of data, and drafting of the article or reviewing it critically for important intellectual content

Critical and timely review of the concept of gastric cytoprotection