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Heatmaps showing z-score normalized median expression levels were created using R package pheatmap, all correlations were performed in R using the packages ggcorrplot, principal component analyses were performed using MMIs for each sample using the stats package in R

In clinical medicine, the difference between n=7 and n=1,877 is the difference between an interesting case series and reliable evidence

Furthermore, DSIP has been shown to have specific anticonvulsant effects in rats

Organs were washed in PBS three times and mounted in SlowFade Gold (S36937, Invitrogen, ThermoFisher)

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