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The study authors suggested that whey encapsulated GSH was better shielded from stomach acid and the digestion by pepsin in the gastrointestinal tract 13 and thus better absorbed.* Whey encapsulated glutathione produced a high surface charge that made the product highly stable and improved absorption.* Finally, whey protein is rich in substrates, which further supported endogenous production of GSH

J Natl Cancer Inst 2001

Azaman, Z

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Here, we provide a systematic discussion of these mechanism by classifying them in alterations (1) that involve steps preceding the binding of cisplatin to DNA (pre-target resistance), (2) that directly relate to DNAcisplatin adducts (on-target resistance), (3) concerning the lethal signaling pathway(s) elicited by cisplatin-mediated DNA damage (post-target resistance) and (4) affecting molecular circuitries that do not present obvious links with cisplatin-elicited signals (off-target resistance)