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Tumor volume was calculated using the formula V = (a 2 b) 0.5, where a represents the short diameter and b the long diameter

NAC is a precursor for the sulfur amino acid cysteine, and cysteine is used by the body to synthesize glutathione

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Covariate analysis showed that body weight appeared to significantly influence clearance, while race influenced volume of distribution

At one month post-operation, isolated cartilage islands were observed, which progressed into more continuous and structured cartilage by six months (Fig