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doi: 10.1038/s41467-019-11665-0

2005 Mar-Apr;49(2):77-82

The concept of targeting specific vasculature for therapeutic purposes has spawned an entire research field

Figure 4 One limitation of examining these clinical trial data in this way is that the ASD population that received the placebo, although similar in development, age and gender, for various reasons, had some differences baseline metabolic characteristics which could affect the effectiveness of the treatment being studied

Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors