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Lassitude symptoms Occurs on a daily basis Is more severe than secondary MS fatigue Is more likely to interfere with daily activities Often occurs early in the morning, even after a restful nights sleep Comes on suddenly and worsens as the day progresses Is aggravated by heat and humidity No matter what form of fatigue an individual with MS may experience, this overwhelming tiredness can affect anyone with MS, regardless of physical disability, and occur at any time in the course of the disease

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Functional centrality of amygdala, striatum and hypothalamus in a small-world network underlying joy: An fMRI study with music

[DOI] [PubMed] [Google Scholar] 192.de Bono J.S., Oudard S., Ozguroglu M., Hansen S., Machiels J.P., Kocak I., Gravis G., Bodrogi I., Mackenzie M.J., Shen L., et al