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Treatment failure often means that the true pain generator has not been fully identified

Changes in eating, such as reduced appetite loss or overeating, represent significant symptoms of severe depression

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In the blood, the early stage of post-ischaemic reperfusion reflects an increase in blood glutamate level, ultimately gaining in oxidative stress and affecting the enzyme antioxidant defence [5, 6]

i did also a test applying on only 1 hand to compare, and we can see the difference