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Plaut and Billow detected the ascorbic acid lowering not only in the organs but also in body fluids as CSF, blood and urine

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J Mol Biol 388:310326

This intervention significantly suppresses the differentiation and inflammatory cytokine production (e.g., IL-17A) of pathogenic Th17 cells, while concurrently promoting the generation of Treg cells (67)

Obviously, VGB4 inhibited VEGF-A induced proliferation of 4T1 cells with a half maximal inhibitory concentration (IC 50 ) of ~0.37 M (Fig