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[DOI] [PMC free article] [PubMed] [Google Scholar] [94].Roth K, Strickland J, Copple BL

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Insulin resistance present in approximately 6580% of cases, independent of body weight, and the primary driver of the androgenic environment in the ovary.[2] Androgen excess elevated testosterone, DHEA-S, or androstenedione, driving most of the visible symptoms: hirsutism, acne, scalp hair thinning, cycle disruption

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Targeted MRM-based methods are most easily developed with the availability of purified proteins, whereas untargeted DDA analyses offer a more flexible, universal application without time-consuming optimization steps