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Together, these results indicate that the Fenton reaction can induce deletion/amplification mutations in target genes during carcinogenesis, presumably through DNA double-stranded breaks (Figure 6)

These results support previous studies in which melatonin, through the activation of the SIRT1 pathway, prevents and protects against neurodegenerative processes, since the benefits include the total preservation of cognitive capacity, protection against amyloid and tau pathology, activation of abnormal protein pathways, and activation of neurotrophy (Sarlak et al., 2013

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5.3.1 Vitamin Microbiota-related vitamins contribute to barrier integrity by regulating tight junctions, epithelial permeability, and epigenetic programs (133, 134)

Pre-vesicular structures, formed by enzymes, oscillate within lysosomes and the VTC complex are essential for vesicle scission