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Ciancarelli, I., Tozzi-Ciancarelli, M., Massimo, C

Furthermore, studies have reported an aberrant activation of NRF2, a key antioxidant transcription factor involved in the regulation of critical antioxidants including glutathione, SOD, and CAT, leading to reduced antioxidant capacity (Hirayama et al., 2020)

Allergic reactions to any of the ingredients are possible, though relatively uncommon given the natural origin of the primary components

Washington, DC: Politics and Prose Publishing

While it is marketed as an effective non-invasive fat reduction method, there are concerns about its safety and a lack of clinical evidence supporting its efficacy, especially when compared to more established alternatives like ultrasound-based treatments such as ULTRAcel Q+