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Description

Suppression of cytokine signaling: the SOCS perspective

There were 2 large human trials with 117 and 320 patients each, but neither showed any benefits after 7-10 days of administration

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Approval status (mixed): Tesamorelin (Egrifta / Egrifta SV) is FDA-approved, but only for HIV-associated lipodystrophy body-composition, muscle and anti-aging use is off-label

Development of selective androgen receptor modulators (SARMs) Selective androgen receptor modulators (SARMs) are tissue-specific activators of the androgen receptor (AR) that offer the therapeutic benefits of androgens with fewer side effects