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Although cancer-associated p53 mutants are capable of binding G6PDH, they are impaired in their ability to inhibit G6PDH activity

One important aspect of lipid peroxidation is the generation of hydroxyl radicals (OH), which can be fatal to cells if they accumulate excessively ( Through an array of procedures, ferroptosis contributes to endothelial cell damage as ARDS progresses ( 3.3 Fibroblast The survival controls for ARDS fibroblasts differ from those for healthy lung fibroblasts