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JHU-083 markedly suppresses the recruitment of MDSCs by decreasing tumor-derived CSF3 levels via degradation of C/EBP, which in turn increases the numbers of proinflammatory TAMs and enhances antigen presentation to CD8(+) T cells, resulting in stronger T-cell responses 150

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J Biol Chem 269: 68426850

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Makinde Applied and Environmental Physiology Unit, Department of Physiology, University of Ibadan, Ibadan, Nigeria Correspondence to: A