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Although analgesics such as NSAIDs are widely used for pain control, they cause some adverse reactions such as upper gastrointestinal bleeding [1, 2, 3]

These include drugs affecting blood cell production (chloramphenicol, anticancer or HIV drugs) and other vitamin and mineral supplements (especially folic acid)

This isn't theoreticalit's demonstrable in substrate availability and downstream signalling

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You should not take vitamin B12 supplements if you have sensitivities or allergies to B12, cobalt, or any other ingredients in the supplement