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Isoflavones (genistein) use both hormonal and non-hormonal action in the prevention of cancer, the hormonal action of isoflavones has been postulated to be through a number of pathways, which include the ability to inhibit many tyrosine kinases involved in regulation of cell growth, to enhance transformation growth factor- which inhibits the cell cycle progression, as well as to influence the transcription factors that are involved in the expression of stress response-related genes involved in programmed cell death

Cai QZ, Lu XZ, Lu Y, Wang AYM (2014) Longitudinal changes of cardiac structure and function in CKD (CASCADE study)

[DOI] [PubMed] [Google Scholar] 63.Liu Y., Fang S., Sun Q., Liu B

Among them, the Nuclear Receptor Co-Repressor (NCoR) stabilizes the closed chromatin state [60] and regulates catabolic processes as well as AR signaling during stress or inflammation of skeletal muscle [61]

1c, when DPCs were treated with 100 g/mL of COE alone, LEF-1 gene expression did not change