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At least, in cisplatin-resistant neuroblastoma cells, CuPDTC can induce cell death and cell cycle arrest by increasing TP53 protein expression, which usually leads to caspase-dependent apoptosis (Zhang et al., 2008)

doi: 10.1016/j.fertnstert.2016.10.008 111 ZhangDYiSCaiBWangZChenMZhengZet al

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N-t-butyl hydroxylamine, a hydrolysis product of -phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts