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The production of ROS from water in the cytoplasm, specifically hydroxyl radicals (OH) and superoxide anions (O 2 ), is induced by ionizing radiation [7]

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And, in a healthy body, 90% of glutathione is found in its reduced, active form

However, if the B12 deficiency causes is more acute or if absorption issues exist, such as pernicious anemia or after surgery to the gastrointestinal tract, vitamin B12 may need to be given intramuscularly

They relieved the thermal and mechanical nociceptive response of OXA-induced painful neuropathy using the tail immersion test in cold water (10C) and the von Frey test (Azevedo et al., 2013)