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Oxidative Stress: An imbalance where reactive byproducts outpace the bodys ability to neutralize them, contributing to cellular strain over time

In diabetic rats, topical administration of HA-coated BSA NPs resulted in a significantly greater fluorescence intensity (12.28 1.39) compared to uncoated NPs (3.55 0.81), achieving 44% of the fluorescence intensity obtained by IVI

Dopamine is involved in motivation and reward circuits, and lower D2 receptor levels may lead to reduced activation of these circuits

It may, however, increase the likelihood of side effects