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Eur J Wildl Res 69(2):32 Matsumura K, Hyon S (2009) Polyampholytes as low toxic efficient cryoprotective agents with antifreeze protein properties

This structure, being non-expandable and tightly associated with the plasma membrane, enables cells to resist the osmotic forces that would otherwise cause swelling and eventually lysis

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Autophagy contributes to cell survival by dismantling dysfunctional mitochondria and decreasing ROS levels, a process contingent upon the hypoxia-induced expression of HIF-1, which involves the HIF-1/BNIP3 signaling pathway (94)