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Interestingly, GPx4 upregulation has been shown to decrease arachidonic acid oxidation products and NF-kB-mediated inflammatory pathways [36], possibly because it is the only GPx that can reduce complex hydroperoxy lipids [21]

Zhang, W., Lang, R

Glutathione S-transferase P-mediated protein S-glutathionylation of resident endoplasmic reticulum proteins influences sensitivity to drug-induced unfolded protein response

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