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Therefore, a deeper understanding of hostpathogen interactions is required to elucidate and validate potential HDTsfor example, recent studies have focused on diverse mechanisms that enhance intracellular survival, including foamy cell induction, modulation of autophagy and phagosome maturation, control of cell death, and manipulation of inflammasome activation in macrophages (262)

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Caspase-cleaved keratin-18 fragments increase during alcohol withdrawal and predict liver-related death in patients with alcoholic liver disease

In cued trials, a 50-ms silent gap was introduced into the background sound 100 ms before the loud noise burst

Conclusion: The COVID-19 pandemic has led to increases in ALD hospitalizations