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D., Luo J

Although PA uses LOX to participate in the ferroptosis process, 15LOX has a significant lack of lipid substrates (159)

Intolerance to even trivial increases in physical or mental activity above individual norms is the hallmark symptom of ME [1012, 17, 18]

Collectively, these findings establish GDH as both a metabolic enzyme and a key regulatory node integrating carbon and nitrogen metabolism with cellular signaling and adaptive responses