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The elevated levels of proinflammatory cytokines and chemokines such as tumour necrosis factor (TNF)-, interleukin 1 (IL-1), IL-6, IL-8 [2,7] and others indicate the cytokine storm plays a central role in the immunopathology of COVID-19, but the primary source or the exact virological mechanisms behind it have not been identified yet [8]

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Anal Biochem 106 : 5562 Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I 2006 Cigarette smoke induces proinflammatory cytokine release by activation of nf-kappab and posttranslational modifications of histone deacetylase in macrophages

Takahashi HK, Santos LR, Roma LP et al (2014) Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic beta-cells

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