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Barcode-based demultiplexing was performed using IDEMP software with default parameters ( Obtained reads were assembled, quality controlled, and clustered using Usearch8.1 software package ( Briefly, reads were merged using -fastq_mergepairs with fastq_maxdiffs 30 and quality filtering was done with fastq_filter (-fastq_maxee 1), minimum read length 200 bp

These symptoms typically diminish over 48 weeks as tolerance develops

reported a deleterious role of IFN- demonstrating reduced demyelination and enhanced remyelination in mice lacking the binding chain of the IFN- receptor (Mana et al., 2006)

The shift to fight or flight happens at the expense of rest and digest. Chronically this might lead to irritable bowel type symptoms, reduction in digestive enzymes and stomach acid, acid reflux, and ultimately gastrointestinal tract dysbiosis, overgrowth, or loss of protective chemistry, et cetera)