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Up to this point, we have ignored the fact that some drugs follow more complex multicompartment pharmacokinetics, eg, the distribution process illustrated by the two-compartment model in Figure 32

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[i] This particular peptide may be found in the bloodstreams of animals naturally, and it has been hypothesized as a potential component in controlling the proliferation, development, and death of vascular endothelial cells

However, it can also be the result of low B6, low folate, renal failure, or hypothyroidism