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The FFA-mediated insulin resistance involves the products of oxidation of FFA in tissues which exacerbates already impaired glucose metabolism (Randle et al., 1965)

When GHRP-2 binds to the GHS-R1a receptors on pituitary somatotrophs (the cells in the pituitary gland that produce GH), it directly signals them to secrete GH

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Neuromodulation Although not universally classified as a classical neurotransmitter, glutathione can influence neural functions: It modulates the redox state of receptors such as the NMDA receptor, consistent with a neuromodulatory role