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Ascorbic acid: its role in the immune system and chronic inflammation diseases

- No blood thinners such as aspirin/ibuprofen 24 hrs before your appointment as this can increase bleeding and swelling

Mulcahy, R.T., et al., Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

Although it has been suggested that metformin treatment may exert a synergistic antitumor effect with ICIs, the study by Jacobi et al (107) did not obtain any positive association between metformin and ICIs in the treatment of patients with diabetes combined with NSCLC

Additional factors including patients preference and administration route must be also taken in consideration