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Description

Redox-active iron, particularly through Fe 3+ /Fe 2+ redox cycling in complexes with amyloid-, can promote the generation of reactive oxygen species (ROS)

Facco, F

30 reported that TRAF6 can increase the chemosensitivity of TNBC to PTX by regulating glycolysis mediated by PKM2

Preclinical studies have confirmed that targeted ferroptosis inhibition alleviates renal injury and fibrosis: 1) deferoxamine mitigates 5/6 nephrectomy-induced CKD in rats via iron metabolism and TGF-1/Smad3 pathway modulation (191)