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Induced pluripotent stem cells restore function in a human cell loss model of open-angle glaucoma

Nat Commun (2023) 14:3673

Schulz (1989) J

Elevated ATF3 expression in aging osteocytes promotes iron uptake by upregulating TFR1 while inhibiting SLC7A11-mediated cystine uptake, leading to iron overload and lipid peroxidation, ultimately resulting in ferroptosis