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Yang B, Xi M, Cui S, et al

The only available human study provides particularly valuable insight into the translational relevance of previously reported findings

It is popular in wellness and performance medicine for its potential benefits in body composition, recovery, and anti-aging, with a favorable safety profile compared to older compounds

Intratracheal NCOA4 siRNA injection in WT mice reduced lipid peroxidation and also reduced CS induced cell death in airway, partially supporting the notion that NCOA4-mediated ferritinophagy has a crucial role in ferroptosis (Supplementary Fig

After a stable infection was established (68 weeks), mice were treated with different antibiotic triple therapies by oral gavage twice a day for 7 days: metronidazole or Metro-P3 (14.2 mg kg 1 day 1 ) or Metro-P3 (0.02 14.2 mg kg 1 day 1 = 0.30 mg kg 1 day 1 ) or MF-01 (0.02 14.2 mg kg 1 day 1 = 0.30 mg kg 1 day 1 ) or metronidazole (0.02 14.2 mg kg 1 day 1 = 0.30 mg kg 1 day 1 ) with clarithromycin (7.15 mg kg 1 day 1 ) or clarithromycin only (control group, 7.15 mg kg 1 day 1 )