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[DOI] [PubMed] [Google Scholar] 66.Simon J.D., Hong L., Peles D.N

Another gap in the knowledge is whether there are potential adverse effects of metformin use in non-diabetics

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Seek immediate medical attention for severe persistent abdominal pain (possible pancreatitis), right upper quadrant pain with fever (gallbladder disease), difficulty breathing or facial swelling (severe allergic reaction), decreased urine output (kidney injury), or inability to keep fluids down for more than 24 hours