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#5 Yes and yes

Whether this translates into meaningfully better athletic recovery outcomes than well-executed oral rehydration depends on the clinical context

Because it is isolated, it can be observed with no fear of light contamination or variability caused by a host star

M.MandelL

This is analogous to how 5-Amino-1MQ works in metabolic research-rather than adding a new signal, it removes a brake on an existing one (NNMT inhibition preserves NAD+