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TBK1s involvement in other types of organelle autophagy and metabolic signaling pathways in immune lineage cells and immune responses is of great interest

24), while MnTCPP + and Zn 2+ alone presented negligible therapeutic effects, as they failed to show antioxidative and anti-inflammatory properties

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2) Cell type- and subtype-specific regulatory blank spots: Most studies have centered on podocytes and TECs, but the role of renal non-parenchymal cells (e.g., mesangial cells, renal endothelial cells, and inflammatory cells) in ferroptosis-driven DN is understudied