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Selective anti-cancer effects of plasma-activated medium and its high efficacy with cisplatin on hepatocellular carcinoma with cancer stem cell characteristics

Previously, it has been shown that iPSCs bearing this mutation express significantly lower GPX4 [35]

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and v ) direct delivery of Cas9-sgRNA assembly or preassembled isolated RNPs into the plant cells

Therefore, the processes resulting in the increase of cellular labile iron, such as uptake transferrin [27, 28], inhibition of the ferroportin exporter [29] and degradation of ferritin [30, 31], will sensitize the cell to lipid peroxidation and eventual cell death