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Ruetten H, Zabel U, Linz W, Schmidt HH

Erectile Dysfunction: Causes and Symptoms Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance

Outcome monitoring should employ validated, condition-specific measures appropriate to the treatment indication

Cellular mechanisms of Decreased Response Desensitization Downregulation Tachyphylaxis Tolerance Desensitization Desensitization refers to a reduced response to an agonist drug due to over activation of a receptor (high doses, prolonged exposure to agonist)

In one double-blind trial comparing GHK-Cu vs Matrixyl 3000, effects reduced wrinkles by 31.6% and improved skin firmness