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doi: 10.1007/s10552-010-9549-y 86

Increased tHcy combined with low B vitamin levels indicates a potential vitamin deficiency: supplement with a multivitamin containing moderate amounts of folic acid (0.2-0.8 mg), B6 (2-25 mg) and B12 (3-100 g/day).18 Switch to high-dose B vitamins only if homocysteine clearly remains elevated and there is no MTHFR mutation (in which case riboflavin or supplementary methyl donors such as 5-MTHF or betaine may lower tHcy)

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It is essential to talk about conditions like liver illness, kidney disease, or a history of allergy to vitamin B12 or other lipotropic medication

For most people, no