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However, several others have emerged and it has been noted that in the majority of cancers, there are no disturbances at the mitochondrial level (130)

2.2 Defective energy metabolism and increased oxidative stress in mitochondria To execute energy production and substance metabolism are the main functions of mitochondria ( + to ultimately initiate OXPHOS

*Correspondence: Tiziana Crepaldi, [email protected] This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Antonoff MB, Correa AM, Sepesi B, Nguyen QN, Walsh GL, Swisher SG , Vaporciyan AA, Mehran RJ, Hofstetter WL, Rice DC

Air particulate matter induced oxidative stress and inflammation in cardiovascular disease and atherosclerosis: the role of Nrf2 and AhR-mediated pathways