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doi: 10.3390/microorganisms11112730 78 XiaoRLeiKKuokHDengWZhuangYTangYet al

Discovery of isoliquiritigenin analogues that reverse acute hepatitis by inhibiting macrophage polarization

As an electrophilic chemical, ITCs might react covalently with the thiol groups of (proteins and) glutathione in plants, similar to what has been demonstrated in different in vitro systems 38,77,78 as well as in insects feeding on GSL or ITC diets 79,80